Liverpool Uveal
Melanoma Prognosticator Online (LUMPO) III
Ver13
Only to be used where medical device regulations exclude prognostication (including UK, USA and Canada) and MUST NOT be used where such tools are regulated as medical devices (e.g. the European Community)
Date:
Patient's Name:
Hospital Number:
Practitioner's
Name:
Position:
Age
years
Epithelioid cells
Sex
Closed PAS +ve loops
Large ultrasound diameter
. mm
Mitotic rate /40
Ultrasound thickness
. mm
Chromosome 3 loss
Ciliary body involvement
Chromosome 8q gain
Extraocular extension
Years since treatment
years
First scan
years
Regional lymph nodes*
Time from Metastasis to death
months
Distant metastasis*
Number needed to scan
* Parameters indicated by an asterisk are
included for TNM staging only and
have no effect on the survival curve
...
Estimated overall survival after treatment for choroidal melanoma
MAM: Metastatic-Associated Mortality, OCM: Other Causes
Mortality
At 5 years, MAM = ..., OCM =
..., chance of survival =
...
At 10 years, MAM = ..., OCM =
..., chance of survival =
...
T:
...
N:
...
M:
...
Stage:
...
Threshold for next scan at: ...
Survival:
Year 1
Year 2
Year 3
Year 4
Year 5
Year 6
Year 7
Year 8
Year 9
Year 10
All causes:
...
...
...
...
...
...
...
...
...
...
Mortality:
Year 1
Year 2
Year 3
Year 4
Year 5
Year 6
Year 7
Year 8
Year 9
Year 10
Metastasis
...
...
...
...
...
...
...
...
...
...
Other causes:
...
...
...
...
...
...
...
...
...
...
Dept. of Medical Physics & Clinical Engineering, Royal Liverpool
University Hospital
Reference: A. Eleuteri, A.F.G. Taktak, S.E. Coupland, H. Heimann, H. Kalirai, B.E. Damato (2018).
Prognostication of metastatic death in uveal melanoma patients: A Markov multi-state model.
Comp Biol Med, 102, pp 151 - 156